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Image Search Results
Journal: British Journal of Pharmacology
Article Title: Preserved arterial vasodilatation via endothelial protease-activated receptor-2 in obese type 2 diabetic mice
doi: 10.1111/j.1476-5381.2011.01356.x
Figure Lengend Snippet: Effects of an AC inhibitor (SQ22536) and PGI 2 receptor antagonist (CAY10441) on 2-furoyl-LIGRLO-amide (2fly)-induced relaxations of db/db and C57BL/6J (C57) mesenteric arteries. Values are the mean ± SE ( n = number of mice) for 2fly-induced relaxations of C57 and db/db second order mesenteric arteries contracted submaximally by U46619 in the absence or presence of (A, B) SQ22536 (100 µM) (C, D) CAY10441 (0.3 µM). Arteries were exposed to inhibitors for 30 min prior to U46619. There were no significant effects of inhibitors or strain on relaxation responses ( P > 0.05, 2-way anova ).
Article Snippet: Other sources included: Bachem (Torrance, CA, USA), charybdotoxin; Cayman Chemicals (Ann Arbor, MI, USA), CAY10441, SC560, SC58125 and
Techniques: